| Item name | Alkaline Phosphatase (ALP) |
|---|---|
| Feature | Alkali phosphatase (ALP) is widely distributed in the cell membranes of living organisms, an enzyme which breaks down various phosphorus compounds in alkali environments as its optimal condition. Since ALP molecules are glycoproteins, there exist several isozymes with different sugar chain structures which are originated from different kind of organs. In the case of abnormal ALP value, an isozyme test is performed to find from which organ it is originated. |
| High value | Liver dysfunction (hepatocirrhosis, acute and chronic hepatitis, etc), cholestasis (acute cholangitis, acute cholestasis, chronic intrahepatic cholestasis, etc.), circumscribed hepatopathy, osteopathy including osteosarcoma |
| Low value | Congenital hypoalkaliphosphatasia |
| Item related to reference | |
| Reference website |
Assay reagent for serum or plasma Cystatin C (Cys C)[PDF]
![Assay reagent for serum or plasma Cystatin C (Cys C)[PDF]](../../imgproduct/sam-cysc.jpg)
In vitro diagnostics
Cys C is a low molecular weight protein whose blood level is little interfered by sex, age and muscle mass, and becomes attention as a novel renal function marker.
Urinal collection, which is needed for creatinine clearance (CCr) test, is not necessary, and only serum (plasma) assay of Cys C enables to evaluate renal function.
The assay is more sensitive and specific to renal function than serum creatinine, and enables to disgnose at early stage of renal dysfunction.
Reagent for albumin measurement (improved BCP method) [PDF]
In vitro diagnostics
This is a reagent which uses the bromcresol purple (BCP) method that has a superior specificity to albumin (oxidized and reduced form) compared to the traditional BCG method.