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  •  Clinical meaning Alkaline Phosphatase (ALP)

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Item name Alkaline Phosphatase (ALP)
Feature Alkali phosphatase (ALP) is widely distributed in the cell membranes of living organisms, an enzyme which breaks down various phosphorus compounds in alkali environments as its optimal condition. Since ALP molecules are glycoproteins, there exist several isozymes with different sugar chain structures which are originated from different kind of organs. In the case of abnormal ALP value, an isozyme test is performed to find from which organ it is originated.
High value Liver dysfunction (hepatocirrhosis, acute and chronic hepatitis, etc), cholestasis (acute cholangitis, acute cholestasis, chronic intrahepatic cholestasis, etc.), circumscribed hepatopathy, osteopathy including osteosarcoma
Low value Congenital hypoalkaliphosphatasia
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